| The Bold Circle App Developers | Johannesburg | Mobile App Development, Performance Marketing | |
| Quickwebsite | Vanderbijlpark | Website design and hosting services | |
| Zarfro Group International | Pretoria | Consulting | |
| Yellow Lizard Creative Strategic Marketing | Port Elizabeth | Advertising / Marketing / Design / Online Marketin | |
| Zania Group | Bloemfontein | Business Development Solutions | |
| Rand4dollar | Sandton | Currency Exchange, Web & Software Development | |
| The Grow Collective | | Full Service Digital Agency | |
| WHITEDROP ENTERPRISE | Bethlehem | Consultants | |
| Sympl Technology Solutions | Midrand | Mobile Apps, Software Development, Data Management | |
| Smart Permission Marketing | Polokwane | COVID-19 Solutions & Resources | |
| Thumbtribe | Ballito | Measurable engagement in store & online | |
| The Training Centre | Cape Town | Software Training - Adobe, Microsoft, Programming | |
| Tech Genius | Brackenfell | Tech Genius | |
| Web Smart | Johannesburg | Digital Marketing | Google AdWords | |
| Rainbow Consulting | Sandton | Marketing management and leadership development | |
| Raque Interactive | Cape Town | Website & Mobile Application Development | |
| Ravensdale IT | Port Elizabeth | Website Development | |
| RDocrat HR Services | Johannesburg | Human Resources and Labour Relations | |
| Re-QUEST Research and Design Solutions | | https://www.linkedin.com/company/re-quest | |
| Readers are Leaders | Cape Town | Direct Marketing in Reading and Language Software | |
| Realce Consulting | Pretoria | Statistical services | |
| RecruitWell Human Capital Solutions | Johannesbuirg | Executive Search ,HR Outsourcing | |
| Redesign IT | | Software Development and IT Solutions | |
| Red Rabbit Media | Johannesburg | Post Production | |
| Rekaofela Youth Development Organisation | Vereeniging | Computer training life skills training, sewing ski | |
| Wilson Web Design and SEO | Cape Town | Web Design/SEO/Hosting | |
| Retail Edge Analytix | Centurion | Consulting | |
| Rockberry Studios | Ballito | Branding and design | |
| Rock & Cricket | Johannesburg | Promotions & Brand Activation Strategy | |
| Rock Solid Consulting | | IT Consultancy,Salesforce,Development,Adobe | |
| Rosemarie Designs | Roodepoort | All things Website and Digital Graphic Design | |
| RSA Learning and Development | Cape Town | Learning Specialist Programme Designer Consulting | |
| RTSquared Communications | Rustenburg | branding, online marketing, business development | |
| Tone Media | Cape Town | Digital Printing, Graphic Design & Web Development | |
| SA Innovation Summit | Johannesburg | Startup support and development | |
| SA Leads | | Lead generation, business development | |
| Saleslogic | Durban | e-Commerce platform | |
| Salt Hospitality Consultants | Cape Town | Hospitality and Retail Consulting Services | |
| SA SchoolCoding | Bellville | Education and support | |
| SA Teen Entrepreneur | Cape Town | Cultivate and promote entrepreneurial spirit | |
| Say Watt | DURBAN | Public Relations | |
| Scarce Graphix | Johannesburg | Multimedia Design, Website Development and Hosting | |
| Scott's Teambuilding Adventures | Westville | Teambuilding | |
| Sea Monster Entertainment | Zonnebloem | 2D Animation, Game Development | |
| Searchable | | Searchable | |
| Search Fusion Online | Durban | SEO, Hosting, Website Development, Design | |
| The Movement Trust | Cape Town | Film & TV Production | |
| Semantica Digital | Cape Town | Semantica Digital (Pty) Ltd | |
| Web SEO | Cape Town | SEO Company and Web Development | |
| Seonomix | Bloubergstrand | Mobile app building, digital news | |
| SEO Traffic | Cape Town | Search Engine Optimization, Local SEO, SEO Package | |
| ServiceGurus | Cape Town | Skills Development, Training and e-learning | |
| Seta Accreditation Services | Ramsgate | Training Provide Accreditation, Skills Development | |
| Shapeshift | Cape Town | Seamless Digital Solutions | |
| Shilin Speed Reading Institute | Johannesburg | Advanced Speed Reading Courses | |
| ShowMe Pretoria | Pretoria | Website Development/Online Marketing | |
| Sichri - Eyewear Straps | Port Elizabeth | accessories | |
| Signa Group | Randburg | B-BBEE Consulting, Services, Solutions | |
| Signa Trust | Randburg | Female Student Support | |
| Sikwantu Npc | Cape Town | Marketing | |
| Simon Barnett Web Design and Development | Cape Town | Front End Web Development, Web Design | |
| Simon Ekin | Cape Town | life coaching, speaking, training | |
| Sirdotcom Technology | Durban | System development and Web applications | |
| Sistersystems | Newcastle | ICT Solutions | |
| Sivatho Chuma Wealth Managers | Mthatha | Business Advisory | |
| Skillset Consulting | Roodepoort | Consulting and training | |
| Skytouch Media | Cape Town | Online Marketing | |
| Sleet Consultancy | Stellenbosch | Copywriting, Proofreading, Social Media, PR | |
| Slif | Johannesburg | Artist Development | |
| Smart Digital Media | Paarl | Web Design, Hosting, Print, Graphic design | |
| Softserve Digital Development | Jhb | We design & develop amazing websites and apps | |
| Software Dev | | Web Development | |
| Software Realisations | South Africa | Software Development | |
| SoftwareXprts | | Info@softwarexprts.com | |
| Solutionsfinding | Pretoria | Whole Brain Solutions | |
| SOMS Digital | Sandton | Digital Marketing Services | |
| Sonja Shear Coaching and Consulting | Johannesburg | Training and coaching | |
| Sonja Shear Coaching and Consulting | Benoni | Business Coaching | |
| Sosys Technologies | Johannesburg | IT and eWaste Management | |
| Source Content Marketing Agency | | Content Marketing | |
| South African Film Empowerment | Pretoria | Film Making and Acting | |
| Southern Spoor | Fourways | Marketing of hotels and lodges | |
| SovTech Software Development | Randburg | SovTech is a custom software development company i | |
| SovTech South Africa | Randburg | Software Development Company | |
| Soweto Express Newspaper | Johannesburg | Advertising | |
| SPACE | Johannesburg | Strategy, Media Planning and Buying, Communication | |
| Specialized Graphics | Centurion | Web Development & Marketing | |
| Spheralytical | | Data Science | |
| Spika | South Africa | Design & illustration | |
| SP Investment Holdings | Johannesburg | strategy; consulting; training and development | |
| Spiral Group | Meyerton | Architect/Draughtsperson | |
| Spiraleye Studios | Highveld Techno Park | Software Multimedia, web, consulting, marketing | |
| SSS Marketing Services | Benoni | Services and Telecommunications | |
| Stained Design | Johannesburg | Design in general - from A to Z | |
| Starbright Solutions | Pretoria | Digital Marketing | |
| Start-Up Mentors | Cape Town | Startup: Business Coaching, Mentoring and Training | |
| Stealth Services | Johannesburg | Web Development | |
