The 13th annual IAB Bookmark Awards took place today in a prestigious virtual celebration. Hosted by the multi skilled Selae Thobakgake and Merica Monamodi; the most thrilling and innovative digital marketing campaigns of the past year were announced.
The winners of the 11th edition of The Radio Awards were announced on today, Friday 30 July 2021, in an online awards ceremony hosted by comedian Loyiso Madinga. A total of 80 winners were celebrated across 30 categories.
Construction on The Capital Mbombela's R205m project, set to be a game-changer on the city's hotel and accommodation industries, is well underway with an anticipated hotel opening set for November 2021.
"The city hasn't seen any significant new additions to its hotel repertoire since development ahead of the 2010 FIFA World Cup projects," says Marc Wachsberger, managing director of The Capital Hotels and Apartments.
"Its status as a leading city in Mpumalanga, at the heart of the province's tourism and agriculture sectors, means that the time is perfect to build an exciting new offering that will be appealing to tourists and corporates alike."
According to a new NielsenIQ report, South Africa's latest liquor ban equated to a loss of R7,6bn during the four weeks it lasted (based on average sales - 13 weeks to end of May 2021 of R1,9bn per week).
An ongoing clinical trial is underway to further evaluate a new tuberculosis (TB) vaccine candidate MTBVAC in an adult endemic population.
MTBVAC is a live, attenuated form of Mycobacterium tuberculosis, the bacterium that causes TB in humans. It therefore might be more effective in preventing TB disease than BCG, the only vaccine currently used to prevent TB, which is derived from a bovine, rather than human, strain of the bacteria.
BCG is effective in preventing severe TB disease in infants and children, but only has a variable effectiveness in disease prevention in adults.
A Phase Ia trial showed that MTBVAC demonstrated a similar safety profile to BCG at a similar dose.
The trial is a collaboration between the University of Zaragoza (Spain), which developed the vaccine candidate; the Spanish biopharmaceutical company Biofabri, which is the vaccine candidate sponsor; the South African Tuberculosis Vaccine Initiative (Satvi); and the TuBerculosis Vaccine Initiative (TBVI). The International Aids Vaccine Initiative (Iavi) is the trial sponsor. Funding is provided by the US National Institutes of Health (NIH) and the US Department of Defense through its Congressionally Directed Medical Research Programme.
Designated A-050, the trial is a Phase Ib/IIa safety and dose-finding study of MTBVAC. This trial is designed to test different doses of MTBVAC and collect additional safety and immunogenicity information in healthy adults with and without evidence of having been previously infected with TB bacteria. It also has the potential to show whether vaccination with MTBVAC produces an immune response distinct from the response to BCG. In A-050, up to 144 participants at Satvi trial site in Worcester, South Africa, will receive either one administration of MTBVAC at different doses or BCG at the standard adult dose. Participants will be monitored for safety and immune response for 12 months after vaccination.
TB is one of the top 10 leading causes of all deaths worldwide and kills about 1.6-million people annually. Each year, about 10-million new cases of TB are detected. The scale of the problem is so great that one in four people globally are infected with the bacteria that cause TB. The World Health Organisation estimates that the annual global economic burden of the TB epidemic is more than $20bn (over R296bn). Experts widely agree that new, more effective TB vaccines will be necessary to address the global TB crisis.
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